Created by: CK-12/Adapted by Christine Miller
The 25-metre long sculpture shown in Figure 4.6.1 is a recognition of the beauty of one of the metabolic functions that takes place in the cells in your body. This artwork brings to life an important structure in living cells: the , the cell structure where are synthesized. The slender silver strand is the messenger (mRNA) bringing the code for a out into the cytoplasm. The purple and green structures are ribosomal subunits (which together form a single ), which can “read” the code on the mRNA and direct the bonding of the correct sequence of amino acids to create a protein. All living — whether they are or — contain , but only eukaryotic cells also contain a and several other types of .
What Are Organelles?
An is a structure within the of a that is enclosed within a membrane and performs a specific job. Organelles are involved in many vital cell functions. Organelles in animal cells include the , , , , , and . are not enclosed within a membrane, but they are still commonly referred to as organelles in cells.
The is the largest organelle in a cell, and it’s considered the cell’s control center. It contains most of the cell’s (which makes up chromosomes), and it is encoded with the genetic instructions for making . The function of the nucleus is to regulate gene expression, including controlling which proteins the cell makes. In addition to DNA, the nucleus contains a thick liquid called , which is similar in composition to the found in the cytoplasm outside the nucleus. Most eukaryotic cells contain just a single nucleus, but some types of cells (such as red blood cells) contain no nucleus and a few other types of cells (such as muscle cells) contain multiple nuclei.
As you can see in the model pictured in Figure 4.6.2, the membrane enclosing the nucleus is called the . This is actually a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm. Tiny holes called allow large molecules to pass through the nuclear envelope, with the help of special proteins. Large proteins and molecules must be able to pass through the nuclear envelope so proteins can be synthesized in the cytoplasm and the genetic material can be maintained inside the nucleus. The nucleolus shown in the model below is mainly involved in the assembly of . After being produced in the , ribosomes are exported to the cytoplasm, where they are involved in the synthesis of proteins.
The mitochondrion (plural, ) is an organelle that makes available to the cell. This is why mitochondria are sometimes referred to as the “power plants of the cell.” They use energy from organic compounds (such as ) to make molecules of (adenosine triphosphate), an energy-carrying molecule that is used almost universally inside cells for energy.
Mitochondria (as in the Figure 4.6.3 diagram) have a complex structure including an inner and out membrane. In addition, mitochondria have their own DNA, ribosomes, and a version of cytoplasm, called matrix. Does this sound similar to the requirements to be considered a cell? That’s because they are!
Scientists think that mitochondria were once free-living organisms because they contain their own . They theorize that ancient prokaryotes infected (or were engulfed by) larger cells, and the two organisms evolved a relationship that benefited both of them. The larger cells provided the smaller prokaryotes with a place to live. In return, the larger cells got extra energy from the smaller prokaryotes. Eventually, the smaller prokaryotes became permanent guests of the larger cells, as inside them. This theory is called , and it is widely accepted by biologists today. (See the video in section 4.3 to learn all about endosymbiotic theory.)
The (ER) is an organelle that helps make and transport and . There are two types of endoplasmic reticulum: (rER) and (sER). Both types are shown in Figure 4.6.4.
- rER looks rough because it is studded with ribosomes. It provides a framework for the ribosomes, which make proteins. Bits of its membrane pinch off to form tiny sacs called vesicles, which carry proteins away from the ER.
- sER looks smooth because it does not have ribosomes. sER makes lipids, stores substances, and plays other roles.
The Figure 4.6.4 drawing includes the nucleus, rER, sER, and Golgi apparatus. From the drawing, you can see how all these organelles work together to make and transport proteins.
The (shown in the Figure 4.6.4 diagram) is a large organelle that processes proteins and prepares them for use both inside and outside the cell. You can see the Golgi apparatus in the figure above. The Golgi apparatus is something like a post office. It receives items (proteins from the ER), then packages and labels them before sending them on to their destinations (to different parts of the cell or to the for transport out of the cell). The Golgi apparatus is also involved in the transport of lipids around the cell.
Vesicles and Vacuoles
Both and are sac-like organelles made of phospholipid bilayer that store and transport materials in the cell. Vesicles are much smaller than vacuoles and have a variety of functions. The vesicles that pinch off from the membranes of the ER and Golgi apparatus store and transport and molecules. You can see an example of this type of transport vesicle in the Figure 4.6.4. Some vesicles are used as chambers for biochemical reactions.
There are some vesicles which are specialized to carry out specific functions. Lysosomes, which use enzymes to break down foreign matter and dead cells, have a double membrane to make sure their contents don’t leak into the rest of the cell. Peroxisomes are another type of specialized vesicle with the main function of breaking down fatty acids and some toxins.
are organelles involved in . The function of centrioles is to help organize the before cell division occurs so that each daughter cell has the correct number of chromosomes after the cell divides. Centrioles are found only in animal cells, and are located near the nucleus. Each centriole is made mainly of a protein named tubulin. The centriole is cylindrical in shape and consists of many microtubules, as shown in the model pictured in Figure 4.6.5.
Ribosomes are small structures where proteins are made. Although they are not enclosed within a membrane, they are frequently considered organelles. Each is formed of two subunits, like the ones pictured at the beginning of this section (Figure 4.6.1) and in Figure 4.6.6. Both subunits consist of proteins and RNA. mRNA from the nucleus carries the genetic code, copied from DNA, which remains in the nucleus. At the ribosome, the genetic code in mRNA is used to assemble and join together amino acids to make proteins. Ribosomes can be found alone or in groups within the cytoplasm, as well as on the rER.
- An is a structure within the cytoplasm of a cell that is enclosed within a membrane and performs a specific job. Although are not enclosed within a membrane, they are still commonly referred to as organelles in eukaryotic cells.
- The is the largest organelle in a eukaryotic cell, and it is considered to be the cell’s control center. It controls gene expression, including controlling which proteins the cell makes.
- The mitochondrion (plural, ) is an organelle that makes energy available to the cells. It is like the power plant of the cell. According to the widely accepted , mitochondria evolved from prokaryotic cells that were once free-living organisms that infected or were engulfed by larger prokaryotic cells.
- The (ER) is an organelle that helps make and transport proteins and lipids. (rER) is studded with ribosomes. (sER) has no ribosomes.
- The is a large organelle that processes proteins and prepares them for use both inside and outside the cell. It is also involved in the transport of lipids around the cell.
- Both and are sac-like organelles that may be used to store and transport materials in the cell or as chambers for biochemical reactions. Lysosomes and peroxisomes are special types of vesicles that break down foreign matter, dead cells, or poisons.
- are organelles located near the that help organize the before so each daughter cell receives the correct number of chromosomes.
- are small structures where proteins are made. They are found in both and cells. They may be found alone or in groups within the or on the rER.
- What is an organelle?
- Describe the structure and function of the nucleus.
- Explain how the nucleus, ribosomes, rough endoplasmic reticulum, and Golgi apparatus work together to make and transport proteins.
- Why are mitochondria referred to as the “power plants of the cell”?
- What roles are played by vesicles and vacuoles?
- Why do all cells need ribosomes — even prokaryotic cells that lack a nucleus and other cell organelles?
- Explain endosymbiotic theory as it relates to mitochondria. What is one piece of evidence that supports this theory?
Biology: Cell Structure I Nucleus Medical Media, Nucleus Medical Media, 2015.
David Bolinsky: Visualizing the wonder of a living cell, TED, 2007.
Mitochondrion_structure.svg by Kelvinsong; modified by Sowlos on Wikimedia Commons is used and adapted by Christine Miller under a CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0) license.
Blausen.com staff. (2014). Nucleus – Medical gallery of Blausen Medical 2014. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. https://en.wikiversity.org/wiki/WikiJournal_of_Medicine/Medical_gallery_of_Blausen_Medical_2014
Blausen.com staff (2014). Centrioles – Medical gallery of Blausen Medical 2014. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436.https://en.wikiversity.org/wiki/WikiJournal_of_Medicine/Medical_gallery_of_Blausen_Medical_2014
Nucleus Medical Media. (2015, March 18). Biology: Cell structure I Nucleus Medical Media. YouTube. https://www.youtube.com/watch?v=URUJD5NEXC8&feature=youtu.be
TED. (2007, July 24). David Bolinsky: Visualizing the wonder of a living cell. YouTube. https://www.youtube.com/watch?v=Id2rZS59xSE&feature=youtu.be
A large complex of RNA and protein which acts as the site of RNA translation, building proteins from amino acids using messenger RNA as a template.
A class of biological molecule consisting of linked monomers of amino acids and which are the most versatile macromolecules in living systems and serve crucial functions in essentially all biological processes.
A nucleic acid of which many different kinds are now known, including messenger RNA, transfer RNA and ribosomal RNA.
The smallest unit of life, consisting of at least a membrane, cytoplasm, and genetic material.
Cells which lack membrane-bound structures, specifically a nucleus. Instead they generally have a single circular chromosome located in an area of the cell called the nucleoid.
Cells which have a nucleus enclosed within membranes, unlike prokaryotes, which have no membrane-bound organelles.
A central organelle containing hereditary material.
A tiny cellular structure that performs specific functions within a cell.
The jellylike material that makes up much of a cell inside the cell membrane, and, in eukaryotic cells, surrounds the nucleus. The organelles of eukaryotic cells, such as mitochondria, the endoplasmic reticulum, and (in green plants) chloroplasts, are contained in the cytoplasm.
A double-membrane-bound organelle found in most eukaryotic organisms. Mitochondria convert oxygen and nutrients into adenosine triphosphate (ATP). ATP is the chemical energy "currency" of the cell that powers the cell's metabolic activities.
A network of membranous tubules within the cytoplasm of a eukaryotic cell, continuous with the nuclear membrane. It often has ribosomes attached and is involved in protein and lipid synthesis.
A membrane-bound organelle found in eukaryotic cells made up of a series of flattened stacked pouches with the purpose of collecting and dispatching protein and lipid products received from the endoplasmic reticulum (ER). Also referred to as the Golgi complex or the Golgi body.
A structure within a cell, consisting of lipid bilayer. Vesicles form naturally during the processes of secretion, uptake and transport of materials within the plasma membrane.
A membrane-bound organelle which is present in all plant and fungal cells and some protist, animal and bacterial cells. It's function is storage of substances and to maintain the rigidity of plant cells.
Deoxyribonucleic acid - the molecule carrying genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses.
A solution, similar to the cytoplasm of a cell, enveloped by the nuclear envelope and surrounding the chromosomes and nucleolus.
The aqueous component of the cytoplasm of a cell, within which various organelles and particles are suspended.
A structure made up of two lipid bilayer membranes which in eukaryotic cells surrounds the nucleus, which encases the genetic material. Also know as the nuclear membrane.
A protein-lined channel in the nuclear envelope that regulates the transportation of molecules between the nucleus and the cytoplasm.
A structure in the nucleus of eukaryotic cells which is the site of ribosome synthesis/production.
The ability to do work.
Glucose (also called dextrose) is a simple sugar with the molecular formula C6H12O6. Glucose is the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight.
A complex organic chemical that provides energy to drive many processes in living cells, e.g. muscle contraction, nerve impulse propagation, and chemical synthesis. Found in all forms of life, ATP is often referred to as the "molecular unit of currency" of intracellular energy transfer.
Any type of a close and long-term biological interaction between two different biological organisms.
An evolutionary theory of the origin of eukaryotic cells from prokaryotic organisms.
A substance that is insoluble in water. Examples include fats, oils and cholesterol. Lipids are made from monomers such as glycerol and fatty acids.
An organelle found in eukaryotic cells. Its main function is to produce proteins. It is a portion of the endoplasmic reticulum which is studded with attached ribosomes.
An organelle found in eukaryotic cells with the function of making cellular products such as hormones and lipids. The smooth endoplasmic reticulum is a part of the endoplasmic reticulum that does not have attached ribosomes.
The semipermeable membrane surrounding the cytoplasm of a cell.
A cylindrical organelle composed of microtubules located near the nucleus in animal cells, occurring in pairs and involved in the development of spindle fibers in cell division.
The process by which a parent cell divides into two or more daughter cells. Cell division usually occurs as part of a larger cell cycle.
A threadlike structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information in the form of genes.